Synthesis of analgesics paracetamol and phenacetin and the sweetener dulcin: a project for undergraduate organic chemistry laboratory

Quimica nova

Baptistella, Lúcia H. B.¹  Imamura, Paulo M.¹  Giacomini, Rosana A.¹ 

[1] Universidade Estadual de Campinas, Campinas

关键词: aromatic compounds;    analgesics paracetamol and phenacetin;    sweetener dulcin.;   

DOI  :  10.1590/S0100-40422003000200024

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

A synthesisof artificial sweetener dulcin starting from nitrobenzene was elaborated forundergraduate organic laboratory course. Paracetamol and phenacetin, both physiologicallyactive analgesic compounds, were also prepared as intermediates. Besides a largescope of discussion subjects related with organic synthesis, interesting lecturesabout analgesics and sweeteners may also be performed in this project. The advantageof this project is the adaptability according to the conditions offered by thecourse, i.e., convenience and/or availability of time and reagents.

【 授权许可】

CC BY