Application of a 33 Box-Behnken Design to Optimize the Extraction of Eleven Fluoroquinolones from Poultry Muscle and Kidney Using a QuEChERS Approach via Liquid Chromatography Tandem Mass Spectrometry: the Easy Use of Microsoft Excel® in Multivariate Analysis

Journal of the Brazilian Chemical Society

Santos, Flavio A.¹  Universidade Federal de Minas Gerais, Belo Horizonte, Brazil¹  Augusti, Rodinei¹  Rocha, Diego G.¹  Ministério da Agricultura, Pecuária e Abastecimento, Pedro Leopoldo, Brazil¹  Faria, Adriana F.¹ 

关键词:  Box-Behnken design;    fluoroquinolones;    QuEChERS;    liquid chromatography;    mass spectrometry;   

DOI  :  10.5935/0103-5053.20150264

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

This work presents an optimization of a quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction approach of eleven fluoroquinolones in poultry muscle and kidney using a 33 Box-Behnken factorial design. All the data treatment was performed using Microsoft Excel® 2010. The suitability of the developed method was confirmed by two proficiency tests for ciprofloxacin and enrofloxacin.

【 授权许可】

Unknown