A novel and simple synthetic route for a piperazine derivative

Journal of the Brazilian Chemical Society

Sousa, Jackson R. de¹  Universidade de São Paulo, São Carlos, Brasil¹  Longhinotti, Elisane¹  Universidade Federal de São Carlos, São Carlos, Brasil¹  Pinheiro, Solange de O¹  Silva, Maria A. S. da¹  Carvalho, Idalina M. M¹  Diógenes, Izaura C. N¹  Francisco, Thiago dos S¹  Silva, Francisco O. N. da¹  Batista, Alzir A¹  Universidade Federal do Ceará, Fortaleza, Brazil¹  Ellena, Javier¹  Dias-Filho, Francisco A¹  Universidade Federal do Ceará, Fortaleza, Brasil¹ 

关键词: piperazine;    nucleophilic addition;    mass spectrometry;    NMR;   

DOI  :  10.1590/S0103-50532010000900023

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A new derivative of piperazine, 5-oxopiperazinium-3-sulfonate monohydrate, was produced from a simple synthetic route as a result of the nucleophilic addition to HSO3- bisulphite ion and of the nucleophilic attack of water molecules on pyrazine molecules. The isolated material was characterized by means of NMR, mass spectrometry, infrared, and X-ray diffraction.

【 授权许可】

Unknown