A novel and simple synthetic route for a piperazine derivative

Journal of the Brazilian Chemical Society

Maria A. S. Da Silva¹  Solange De O Pinheiro¹  Thiago Dos S Francisco¹  Francisco O. N. Da Silva¹  Alzir A Batista²  Javier Ellena²  Idalina M. M Carvalho¹  Jackson R. De Sousa¹  Francisco A Dias-filho¹  Elisane Longhinotti²  Izaura C. N Diógenes¹ 

[1] ,Universidade Federal do Ceará Departamento de Química Orgânica e Inorgânica Fortaleza CE ,Brazil

关键词: piperazine;    nucleophilic addition;    mass spectrometry;    NMR;   

DOI  :  10.1590/S0103-50532010000900023

来源: SciELO

【 摘 要 】

A new derivative of piperazine, 5-oxopiperazinium-3-sulfonate monohydrate, was produced from a simple synthetic route as a result of the nucleophilic addition to HSO3- bisulphite ion and of the nucleophilic attack of water molecules on pyrazine molecules. The isolated material was characterized by means of NMR, mass spectrometry, infrared, and X-ray diffraction.

【 授权许可】

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