Antioxidant and antimicrobial properties of 2-(4,5-dihydro-1H-pyrazol-1-yl)-pyrimidine and 1-carboxamidino-1H-pyrazole derivatives

Journal of the Brazilian Chemical Society

Moura, Sidnei¹  Flores, Alex F. C.¹  Colepicolo, Pio¹  Pinto, Ernani¹  Gressler, Vanessa¹  Flores, Darlene C.¹  Universidade de São Paulo, São Paulo, Brazil¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: heterocycles;    4;    5-dihydropyrazoles;    antioxidant activity;    antimicrobial activity;   

DOI  :  10.1590/S0103-50532010000800010

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Five previously synthesized 4-trifluoromethyl-2-(5-aryl-3-styryl-1H-pyrazol-1yl)-pyrimidines and six 5-aryl-3-styryl-1-carboxamidino-1H-pyrazole derivatives were screened for their antioxidant proprieties. The antioxidant activities were evaluated by using the DPPH and the HRP/luminol/H2O2 chemiluminescence assay systems and for their antimicrobial activity (MIC). The results were good for those series in some concentration in comparison with the standards.

【 授权许可】

Unknown