Lippia sidoides essential oil encapsulation by angico gum/chitosan nanoparticles

Journal of the Brazilian Chemical Society

Paul, Regina C. M. de¹  Sombra, Fernanda M.¹  Universidade Federal do Ceará, Fortaleza, Brazil¹  Abreu, Flávia O. M. S¹  Paula, Haroldo C. B.¹ 

关键词: nanoparticles;    chitosan;    angico gum;    essential oil;    encapsulation;   

DOI  :  10.1590/S0103-50532010001200025

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Chitosan (CH) and angico gum (AG) nanoparticles were loaded with essential oil, Lippia sidoides (Ls), being characterized according to their composition, size distribution, Ls:polymer ratio, thermal stability and in vitro and in vivo controlled release. Nanoparticles prepared using Ls:AG ratios of 1:2 to 1:20 had loading values of 3.3 to 7.7%, with encapsulation efficiencies in the range of 16.0 to 77.8%. Particle sizes were in the range of 10-60 nm and size distributions were independent of Ls content, for different Ls:AG ratios. Infrared spectroscopy revealed the presence of thymol in the nanoparticles. TGA and DSC revealed that the degradation temperature of AG-CH nanoparticles decreased with an increase in Ls content. Controlled-release data showed a slower release profile for samples with Ls:AG = 1:10 than for the other samples. Bioassays showed that sample Ls:AG = 1:10 has a greater larvicidal effect, with 85 ± 3% mortality.

【 授权许可】

Unknown