期刊论文详细信息
Journal of the Brazilian Chemical Society
Preparation of novel trifluoroacetylketene O,N-acetals and trifluoromethyl-containing S,S-sulfoximido N-substituted heterocycles
Vezzosi, Renata P.1  Rodrigues, Isadora R.1  Flores, Alex F. C.1  Porte, Liliane M. F.1  Zanatta, Nilo1  Drekener, Roberta L.1  Bonacorso, Helio G.1  Martins, Marcos A. P.1  Universidade Federal de Santa Maria, Santa Maria, Brazil1 
关键词: acetals;    sulfoximides;    pyrazoles;    isoxazoles;    pyrimidines;   
DOI  :  10.1590/S0103-50532009000700024
学科分类:化学(综合)
来源: SciELO
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【 摘 要 】

Two new trifluoroacetylketene O,N-acetals [CF3C(O)CH=C(OEt)(NS(O)R2), where R = CH3, Ph] derived from the reaction of 4,4-diethoxy-1,1,1-trifluorobut-3-en-2-one [CF3C(O)CH=C(OEt)2] with S,S-dimethyl- and S-methyl-S-phenyl-sulfoximide [HN=S(O)R2], in the presence of triethylamine, have been obtained, in 60-72% yields, and applied in the synthesis of S,S-dimethylsulfoximido-substituted pyrazoles, isoxazoles and pyrimidines, in 55-89% yields, from the reactions of 4-ethoxy-4-(S,S-dimethylsulfoximido)-1,1,1-trifluorobut-3-en-2-one with hydrazines, hydroxylamine hydrochloride and acetylguanidine.

【 授权许可】

Unknown   

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