Dihydroflavonols from the leaves of Derris urucu (Leguminosae): structural elucidation and DPPH radical-scavenging activity

Journal of the Brazilian Chemical Society

Santos, Alberdan S.¹  Campus Universitário do Guamá, Belém, Brazil¹  Silva, Geilson A. da¹  Borges, Rosivaldo dos Santos¹  Silva, Milton N. da¹  Guilhon, Giselle M. S. P.¹  Lôbo, Lívia T.¹  Ferreira, Malisson¹  Universidade Federal do Pará, Belém, Brazil¹  Santos, Lourivaldo S.¹  Arruda, Alberto C.¹  Arruda, Mara Silvia P.¹ 

关键词: Derris urucu;    Leguminosae;    dihydroflavonols;    radical scavenging activity;    antioxidant;   

DOI  :  10.1590/S0103-50532009000600013

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Derris urucu is an Amazonian plant with insecticide and ichthyotoxic properties. Studies with this species show the presence of flavonoids, mainly rotenoids, as well as stilbenes. The ethanol extract of the leaves of Derris urucu (Leguminosae) afforded three new dihydroflavonols named urucuol A (1), B (2) and C (3), and the dihydroflavonol isotirumalin (4). Their structures were elucidated by extensive analysis of 1D and 2D NMR, UV and IR spectra and MS data and comparison with literature data. The isolated compounds (1-4) were evaluated for DPPH• radical scavenging activity and showed a relatively lower antioxidant ability compared to the commercial antioxidant trans-resveratrol.

【 授权许可】

Unknown