Electrospray ionization mass spectrometry screening of piperidine alkaloids from Senna spectabilis (Fabaceae) extracts: fast identification of new constituents and co-metabolites

Journal of the Brazilian Chemical Society

Universidade de Franca, Franca, Brazil¹  Universidade de São Paulo, Ribeirão Preto, Brazil¹  Rezende, Amanda de¹  Castro-Gamboa, Ian¹  Lopes, Norberto P.¹  Viegas Jr., Cláudio¹  Furlan, Maysa¹  Instituto de Botânica, São Paulo, Brazil¹  Pivatto, Marcos¹  Young, Maria Claudia M.¹  Crotti, Antônio E. M.¹  Bolzani, Vanderlan S.¹  Universidade Estadual Paulista, Araraquara, Brazil¹ 

关键词: Senna spectabilis;    piperidine alkaloids;    metabolomic profile;    electrospray;    tandem mass spectrometry;   

DOI  :  10.1590/S0103-50532005000800023

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The fragmentation pattern of a homologous series of piperidine alkaloids isolated from S. spectabilis was investigated using electrospray ionization tandem mass spectrometry (ESI-MS/MS). The ESI-MS and ESI-MS/MS analyses of EtOH extracts and fractions from flowers and fruits of S. spectabilis allowed to elucidate the structures of four new compounds. The identification of these co-metabolites, based on the fragmentation patterns of previously isolated compounds, and further confirmed by accurate mass spectrometry defines this technique as a powerful tool to determine the "metabolomic profile" of species which has pharmacological importance.

【 授权许可】

Unknown