Comparative study of structure: activity relationship of di and triorganotin (IV) complexes of monomethyl glutarate

Journal of the Brazilian Chemical Society

Rehman, Wajid¹  Baloch, Musa Kaleem¹  Quaid-e-Azam University, Islamabad, Pakistan¹  Badshah, Amin¹  Gomal University, Dera Ismail Khan, Pakistan¹ 

关键词: organotin(IV);    monomethyl glutarate;    biological activity;   

DOI  :  10.1590/S0103-50532005000500023

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A series of di and triorganotin(IV) complexes of monomethyl glutarate have been synthesized and characterized through 1H 13C 119Sn NMR, FT-IR and 119Sn Mössbauer spectroscopy. On the basis of these techniques, it is proposed that the ligand molecule is bound to the tin atom through the carbonyl oxygen. The data reveal that diorganotin(IV) complexes exhibit hexa-coordination with octahedral geometry, while triorganotin(IV) complexes have penta-coordination with trigonal bipyramidal geometry. Biological evaluation against various microorganisms indicate that diorganotin(IV) complexes are less active than the triorganotin(IV) complexes.

【 授权许可】

Unknown