Effects of Escitalopram on Autonomic Function in Posttraumatic Stress Disorder Among Veterans of Operations Enduring Freedom and Iraqi Freedom (OEF/OIF)

Innovations in Clinical Neuroscience

David Driscoll¹  Vithyalakshmi Selvaraj¹  Jayakrishna S. Madabushi¹  Vikram Yeragani¹  Subhash C. Bhatia¹  Sriram Ramaswamy¹ 

[1] Drs. Ramaswamy, Driscoll, and Bhatia are with the Nebraska Western Iowa Veterans Affairs Healthcare System and Creighton University, Omaha, Nebraska; Dr. Selvaraj is with Creighton University, Omaha, Nebraska; Dr. Madabushi is with Baptist Health System, Birmingham, Alabama; and Dr. Yeragani is with Wayne State University School of Medicine, Detroit, Michigan, and the University of Alberta, Edmonton, Canada

关键词: PTSD;    posttraumatic stress disorder;    depression;    sympathetic;    vagal;    heart rate variability;    spectral analysis;    QT variability;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Objective: Posttraumatic stress disorder is a chronic, debilitating condition that has become a growing concern among combat veterans. Previous research suggests that posttraumatic stress disorder disrupts normal autonomic responding and may increase the risk of cardiovascular disease and mortality. Measures of heart rate variability and QT interval variability have been used extensively to characterize sympathetic and parasympathetic influences on heart rate in a variety of psychiatric populations. The objective of this study was to better understand the effects of pharmacological treatment on autonomic reactivity in posttraumatic stress disorder.

【 授权许可】

Unknown