The Direct and Indirect Effects of Paliperidone Extended-release on Depressive Symptoms in Schizoaffective Disorder: A Path Analysis

Innovations in Clinical Neuroscience

Dong-Jing Fu¹  Larry Alphs¹  Ibrahim Turkoz¹  Cynthia A. Bossie¹ 

[1] Dr. Turkoz is with Janssen Research and Development LLC, Titusville, New Jersey, USA, and Drs. Fu, Bossie, and Alphs are with Janssen Scientific Affairs LLC, Titusville, New Jersey, USA.

关键词: Paliperidone;    schizoaffective disorder;    depressive symptoms;    path analysis;    direct effects;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Background: This analysis evaluates improvement in symptoms of depression in patients with schizoaffective disorder administered oral paliperidone extended-release by accounting for the magnitude of direct and indirect (changes in negative and positive symptoms and worsening of extrapyramidal symptoms) treatment effects on depressive symptoms.

【 授权许可】

Unknown