A Risperidone-Induced Prolactinoma Resolved when a Woman with Schizoaffective Disorder Switched to Ziprasidone: A Case Report

Innovations in Clinical Neuroscience

Gail T. Arcari¹  Asante K. Mendes¹  Robert B. Sothern¹ 

[1] Ms. Arcari is from Cromwell, Connecticut; Dr. Mendes is from Tufts University School of Medicine, Boston, Massachussetts, and University of Connecticut Health Center, Farmington, Connecticut; and Dr. Sothern is Research Assistant Professor, College of Biological Sciences, University of Minnesota, St. Paul, Minnesota.

关键词: Prolactinoma;    schizoaffective disorder;    mania;    risperidone;    ziprasidone;    pituitary tumor;    prolactin;   

DOI  :  

学科分类：精神健康和精神病学

来源: Matrix Medical Communications, LLC

【 摘 要 】

Antipsychotic drug therapy, e.g., risperidone, can be associated with endocrine abnormalities, including an increase in serum prolactin level (sPrl) due to a drug-induced benign pituitary tumor (prolactinoma). A few case reports have noted a resolution of hyperprolactinemia and prolactinoma after cessation of risperidone treatment. We report a similar finding for a woman with schizoaffective disorder, manic type.

【 授权许可】

Unknown