Medical Management of Lower Urinary Tract Symptoms

Reviews in Urology

Eric E Laborde¹  Kevin T McVary¹ 

[1] Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL

关键词: 5α-reductase inhibitors;    α-Blockers;    Anticholinergics;    Benign prostatic hyperplasia;    Combination therapy;    Lower urinary tract symptoms;    Phosphodiesterase type 5 inhibitors;   

DOI  :  

学科分类：基础医学

来源: MedReviews, LLC

【 摘 要 】

Lower urinary tract symptoms (LUTS) are a common complaint among aging men and are often caused by benign prostatic hyperplasia (BPH). A number of medical treatments for LUTS/BPH exist, such as α-blockers, 5α-reductase inhibitors, anticholinergics, phosphodiesterase type 5 (PDE5) inhibitors, and combination therapies. Agonist binding of the α1A-adrenergic receptor (AR), causing prostatic smooth muscle contraction, has been attributed to cause some LUTS. Therefore, medical therapy has aimed to block the α1A-AR and improve LUTS. Determining which therapy to choose must take into account individual patient factors as well as cost and patient choice.

【 授权许可】

Unknown