AgNOR histochemical expression in benign prostatic hyperplasia and prostatic adenocarcinoma

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Rita, R.^1 ; Delyuzar^1 ; Laksmi, L.I.^1

Anatomical Pathology Department, Universitas Sumatera Utara, Medan, Indonesia^1

关键词: Benign prostatic hyperplasia;    Common disease;    Descriptive studies;    Immunohistochemical staining;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012220/pdf
DOI  :  10.1088/1755-1315/125/1/012220

来源: IOP

【 摘 要 】

Benign prostatic hyperplasia and prostatic adenocarcinoma were common diseases and usually occurred after the 5thdecade of life. The problem in diagnosing using Hematoxylin and Eosin staining was how to differentiate whether it is benign or malignant zone. Therefore, proliferating markers, such as AgNOR, could be helping to over this difficulty. A descriptive study using consecutive sampling as the method of sample recruiting was conducted to describe AgNOR histochemical expression in benign prostatic hyperplasia and prostatic adenocarcinoma. AgNOR staining was done in 13 benign prostatic hyperplasia samples and 7 prostatic adenocarcinoma samples, which have been confirmed using p63 immunohistochemical staining before. Benign prostatic hyperplasia usually showed lower AgNOR proliferating activity while all of theprostatic adenocarcinoma (100%) had high AgNOR proliferating activity.