Sexual Function and α-Blockers

Reviews in Urology

Kevin T McVary¹ 

[1] Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL

关键词: Benign prostatic hyperplasia;    Lower urinary tract symptoms;    Sexual dysfunction;    α-Blockers;    Sildenafil;   

DOI  :  

学科分类：基础医学

来源: MedReviews, LLC

【 摘 要 】

Community-based studies and surveys have found an association between lower urinary tract symptoms (LUTS) and sexual dysfunction, in particular, erectile dysfunction (ED). The link between ED and LUTS has biologic plausibility. The following 4 theories have been used to explain how these disorders interrelate: 1) decreased or altered nitric oxide synthase/nitric oxide levels in the prostate and penile smooth muscle; 2) autonomic hyperactivity effects on LUTS, prostate growth, and ED; 3) increased Rho-kinase activation/endothelin activity; and 4) prostate and penile atherosclerosis. The relationship of LUTS and sexual dysfunction suggests that treatment of one condition may impact the other.

【 授权许可】

Unknown