Glomerulocystic Kidney Disease and Hepatoblastoma in an Infant: A Rare Presentation

Cardiorenal Medicine

Divya-Devi Joshi¹  Alec Maggi¹  Rumina Zaman¹  Sudeep K. Rajpoot¹ 

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关键词: Hepatoblastoma;    Beckwith-Wiedemann syndrome;    Glomerulocystic kidney disease;    Hepatocyte growth factor;    Insulin-like growth factors;   

DOI  :  10.1159/000439520

来源: S Karger AG

【 摘 要 】

Glomerulocystic kidney disease (GCKD) is a rare condition comprising heritable and nonheritable types [Oh et al.: Nephron 1986;43:299-302]. Hepatoblastoma is a sporadically occurring tumor of embryonal origin that is associated with overgrowth syndrome and renal cysts. A concurrent presentation of GCKD with hepatoblastoma was first described in 1989 [Rao et al.: Jpn J Surg 1989;19:583-585]. We report the simultaneous presentation of hepatoblastoma and GCKD in a 5-month-old child and explore the probability of insulin-like growth factors, insulin-like growth factor-binding protein and Beckwith-Wiedemann gene mutation as a putative cause.

【 授权许可】

Unknown