A mild and highly chemoselective iodination of alcohol using polymer supported DMAP

Journal of Chemical Sciences

DIPARJUN DAS²  LALTHAZUALA ROKHUM1²  JASHA MOMO H ANAL¹ 

[1] Department of Chemistry, North Eastern Hill University, Shillong, Meghalaya 793 022, India$$;Department of Chemistry, National Institute of Technology, Silchar, Assam 788 010, India$$

关键词: Iodination;    Polymer supported DMAP;    Triphenylphosphine;    Iodine;    Catalyst;    Chemoselective;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

The synthesis of organic compounds using polymer supported catalysts and reagents, where the required product is always in solution, has been of great interest in recent years, both in industries and academia especially in pharmaceutical research. Here, a simple and efficient method for conversion of alcohols into their iodides in high yield using polymer supported 4-(Dimethylamino)pyridine (DMAP) is described. Polymer supported DMAP is used in catalytic amount and is recovered and reused several times. Additionally, this method is highly chemoselective.

【 授权许可】

Unknown