A comparative study of Cu(II)-assisted vs Cu(II)-free chalcogenation on benzyl and 2°/3°-cycloalkyl moieties

Journal of Chemical Sciences

Santosh K Sahoo1¹ 

[1] Department of Chemistry, Indian Institute of Technology - Bombay, Powai, Mumbai 400 076, India$$

关键词: C-H functionalization;    C-Chalcogen bond formation;    metal vs. metal free condition;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

A relative synthetic strategy toward intermolecular oxidative C−Chalcogen bond formation of alkanes has been illustrated using both Cu(II) assisted 𝑣𝑠 Cu(II) free conditions. This led to construction of a comparative study of hydrocarbon benzylic and 2°/3°-cycloalkyl moieties bond sulfenylation and selenation protocol by the chalcogen sources, particularly sulfur and selenium, respectively. In addition, this protocol disclosed the auspicious formation of sp3C−S coupling products over leading the sp3C−N coupling products by using 2-mercaptobenzothiazole (MBT) substrates.

【 授权许可】

Unknown