期刊论文详细信息
Journal of Chemical Sciences | |
Asymmetric synthesis of a functionalized tricyclo[6.2.0.02,6]decane ring system present in kelsoene and poduran | |
Amrita Ghosh1  Subrata Ghosh11  | |
[1] Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India$$ | |
关键词: Asymmetric synthesis; cycloaddition; metathesis; terpenes.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
Synthesis of a functionalized tricyclo[6.2.0.02,6]decane derivative in enantiomerically pure form, the core structure present in the natural products kelsoene and poduran, is described. The key steps involve a stereocontrolled copper (I)-catalyzed intramolecular [2+2] photocycloaddition of a 1, 6-diene prepared from D-mannitol to form a substituted bicyclo[3.2.0]heptane derivative and a ring closing olefin metathesis involving the vicinal substituents on the five-membered ring of the bicyclo[3.2.0]heptane derivative.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201912040508859ZK.pdf | 519KB | download |