期刊论文详细信息
Journal of Chemical Sciences | |
Synthesis of 2-(oxadiazolo, pyrimido, imidazolo, and benzimidazolo) substituted analogues of 1,4-benzodiazepin-5-carboxamides linked through a phenoxyl bridge | |
N Kaur11  D Kishore1  | |
[1] Department of Chemistry, Banasthali University, Banasthali-304022 (Rajasthan), India$$ | |
关键词: 1; 4-benzodiazepine; oxadiazole; pyrimidine; imidazole; benzimidazole; amidine and imidate ester.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
Exceedingly facile single-step expedient protocols based on the versatility and reactivity of corresponding intermediates amidine and imidate (8 and 9), derived from 5-carboxamido-1,4-benzodiazepin-5-(4'-methylpiperazinyl)-carboxamide have been developed to provide an easy installation of the oxadiazole, pyrimidine, imidazole and benzimidazole (9-14) based privileged templates at 2-position of 5-carboxamido-1,4-benzodiazepin-5-(4'-methylpiperazinyl)-carboxamide (4), through a phenoxyl spacer, by utilizing the synthetic strategy depicted in schemes 1 and 2.
【 授权许可】
Unknown
【 预 览 】
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