Water mediated eco-friendly green protocol for one-pot synthesis of 𝛼-aminophosphonates at ambient conditions

Journal of Chemical Sciences

Manjula Alla1¹  Santhosh Reddy Mandha¹  Vittal Rao Bommena¹ 

[1] Crop Protection Chemicals, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India$$

关键词: 𝛼-Aminophosphonates;    aldehydes;    amines;    trimethyl phosphite;    solvent-free.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Increasing environmental awareness and economic concerns have led to the consideration of highly efficient one-pot, three-component, green approaches for important organic synthons. We describe here a simple, elegant and high yielding protocol for the synthesis of 𝛼-aminophosphonates in totally solvent-free, catalyst-free conditions by reacting aldehydes, amines and trimethyl phosphite at ambient temperature.

【 授权许可】

Unknown