期刊论文详细信息
Journal of Chemical Sciences | |
A new one-pot synthesis of 1,2,4-oxadiazoles from aryl nitriles, hydroxylamine and crotonoyl chloride | |
Majid M Heravi22  Ebrahim Abouzari-Lotf3  Masoumeh Zakeri11  | |
[1] Young Researchers and Elites Club, North Tehran Branch, Islamic Azad University, Tehran 15742, Iran$$;Department of Chemistry, School of Sciences, Alzahra University, 1993891176, Vanak, Tehran, Iran$$;Institute of Hydrogen Economy, Energy Research Alliance, International Campus, Universiti Teknologi Malaysia, Kuala Lumpur 54100, Malaysia$$ | |
关键词: 1; 2; 4-Oxadiazole; crotonoyl chloride; amidoxime; hydroxylamine.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
The reaction of aryl nitriles with hydroxylamine using acetic acid as a catalyst followed by subsequent addition of crotonoyl chloride to the intermediate amidoxime represents a straightforward one-pot access to new 1,2,4-oxadiazole synthesis under mild conditions. The course of the reaction was found to be high yielding and all new compounds were well characterized by nuclear magnetic resonance (NMR), mass spectrometry (MS) and elemental analysis.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201912040508559ZK.pdf | 275KB | download |