Synthesis of a series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as potential antioxidant and antibacterial agents

Journal of chemical biology

M. Aruna Sindhe¹ 

关键词: 1;    3;    4-Oxadiazole;    Antimicrobial;    Antioxidant;    Molecular docking;   

DOI  :  10.1007/s12154-016-0153-9

学科分类：分子生物学，细胞生物学和基因

来源: Springer

【 摘 要 】

A series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and screened for their antimicrobial and antioxidant activities. The assay indicated that compounds 3c, 3d, and 3i exhibited comparable antibacterial and antioxidant activity with first-line drugs. The structure activity relationship and molecular docking study of the synthesized compounds are also reported.

【 授权许可】

CC BY