Synthesis and antibacterial activity of sulfonamide derivatives at C-8 alkyl chain of anacardic acid mixture isolated from a natural product cashew nut shell liquid (CNSL)

Journal of Chemical Sciences

V Ravi Kumar¹  M Adharvana Chari3 4²  N Subhakara Reddy1¹  V Himabindu³  A Srinivas Rao¹  V Jyothy² 

[1] Medicinal chemistry Laboratory, GVK Biosciences Pvt Ltd, Plot No 5C, IDA, Uppal Road, Hyderabad 500 039, India$$;Dr. MACS Bio-Pharma Pvt. Ltd., Plot-32/A,Westren Hills, Kukatpally, Hyderabad 500 085, India$$;Centre for Environment, Institute of Science and Technology, JNT University, Kukatpally, Hyderabad 500 085, India$$

关键词: Synthesis;    sulfonamide derivatives;    anacardic acid;    antibacterial activity.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Synthesis and antibacterial activity of some novel biologically active sulfonamide derivatives at C-8 alkyl chain of anacardic acid (7a-7l), prepared from commercially available anacardic acid mixture (1a-d). These compounds were tested for Gram positive and Gram negative bacterial cultures; most of the compounds showed higher antibacterial activity compared with standard drug ampicillin.

【 授权许可】

Unknown