期刊论文详细信息
Journal of Chemical Sciences | |
Synthesis and anti-inflammatory activity of 3-indolyl pyridine derivatives through one-pot multi component reaction | |
Paramasivan T Perumal11  Prakasam Thirumurugan1  S Mahalaxmi1  | |
[1] Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai 600 020$$ | |
关键词: Multi component reaction; 3-cyanoacetyl indole; malononitrile; pyridine synthesis; antiinflammatory activity; analgesic activity.; | |
DOI : | |
来源: Indian Academy of Sciences | |
【 摘 要 】
A simple protocol for the efficient preparation of 2-(1ð»-Indol-3-yl)-6-methoxy-4-arylpyridine-3,5-dicarbonitrile has been achieved through one-pot multi-component reaction under reflux condition. These compounds showed a good anti-inflammatory activity. Also a series of bis-Hantzsch dihydropyridine derivatives were synthesized and they exhibit analgesic activity.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912040508203ZK.pdf | 547KB | download |