Spectral, magnetic and biological studies of 1,4-dibenzoyl-3-thiosemicarbazide complexes with some first row transition metal ions

Journal of Chemical Sciences

Anuraag Shrivastav¹  Saty B Singh¹  Sukh M Singh²  Nand K Singh1¹ 

[1] Department of Chemistry, Banaras Hindu University, Varanasi 221 005, India$$;School of Biotechnology, Banaras Hindu University, Varanasi 221 005, India$$

关键词: 3𝑑-Metal complexes;    thiosemicarbazide;    antitumour activity.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

The ligand 1,4-dibenzoyl-3-thiosemicarbazide (DBtsc) forms complexes [M(DBtsc-H)(SCN)] [M = Mn(II), Co(II) or Zn(II)], [M(DBtscH)(SCN)(H2O)] [M = Ni(II) or Cu(II)], [M(DBtsc-H)Cl] [M = Co(II), Ni(II), Cu(II) or Zn(II)] and [Mn(DBtsc)Cl2], which have been characterized by elemental analyses, magnetic susceptibility measurements, UV/Vis, IR, 1H and 13C NMR and FAB mass spectral data. Room temperature ESR spectra of the Mn(II) and Cu(II) complexes yield values, characteristic of tetrahedral and square planar complexes respectively. DBtsc and its soluble complexes have been screened against several bacteria, fungi and tumour cell lines.

【 授权许可】

Unknown