Determination of the Lipophilicity of Some New Derivatives of Thiosemicarbazide and 1,2,4-triazoline-5-thione with Potential Antituberculosis Activity

Croatica Chemica Acta

Ginalska, Grażyna¹  Polak, Beata³  Pitucha, Monika²  Popiołek, Łukasz²  Swatko-Ossor, Marta¹ 

[1] Department of Biochemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 1, 20-093 Lublin, Poland;Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Staszica 6, 20-081 Lublin, Poland;Department of Physical Chemistry, Chair of Chemistry, Faculty of Pharmacy, Medical University of Lublin, Staszica 6, 20-081 Lublin, Poland

关键词: thiosemicarbazide;    1;    2;    4-triazoline-5-thione;    Mycobacterium tuberculosis;    lipophilicity;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

The chromatographic behavior of newly obtained derivatives of thiosemicarbazide and 1,2,4- triazoline-5-thione was determined. The lipophilicity was confirmed by the use of the Reversed Phase Thin-Layer Chromatography (RP-TLC) method....

【 授权许可】

Unknown