Oriental Pharmacy and Experimental Medicine | |
Phytochemical screening and pharmacological activities of Ulmus campestris bark extracts | |
Hania Boudaoud-Ouahmed1  Djebbar Atmani1  Sid-Ali Tiab1  Keltoum Ziane1  Nabil Saidani1  Mehdi Gherrou1  | |
[1] Université de Bejaia$$ | |
关键词: Ulmus campestris; | |
DOI : 10.1007/s13596-015-0209-3 | |
学科分类:药学 | |
来源: Springer | |
【 摘 要 】
Ulmus campestris (Ulmaceae) is a medicinal plant traditionally used to treat various ailments, including inflammatory diseases. In order to establish pharmacological properties of Ulmus campestris bark extracts obtained with a selective extraction procedure, several studies were performed. Results showed strong scavenging activity of extracts against DPPH (IC50 = 03.90 μg/ml), hydrogen peroxide (IC50 = 71.05 μg/ml), hydroxyl (IC50 = 40.13 μg/ml), hypochlorous acid (IC50 < 100 μg/ml) and ABTS•+ (IC50 = 12.16 μg/ml) radicals. Moreover, U. Campestris extracts inhibited lipid peroxidation (52.60 ± 0.37 %) and xanthine oxidase activity (IC50 = 285.25 μg/ml) effectively. The crude extract of U. campestris extract (400 mg/kg) exhibited a significant effect (50.60 %) on carrageenan-induced inflammation, acetic acid-induced writhing (33.68 %) and on tail immersion (73.00 %) tests. The extract was also effective on brewer’s yeast-induced fever. Obtained results may well explain the use of U. campestris in folk medicine, especially in the treatment of pain, gout and inflammatory diseases.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912040506327ZK.pdf | 113KB | download |