Shape variation of bilayer membrane daughter vesicles induced by anisotropic membrane inclusions

Cellular & Molecular Biology Letters

Sylvio May¹  Miha Fošnarič⁴  Aleš Iglič⁴  Henry Hägerstrand²  Klemen Bohinc⁵  Franjo Pernuš⁴  Darko Lombardo⁴  Veronika Kraljiglič³ 

[1]Department of Physics, North Dakota State University, Fargo, USA$$

[2]Department of Biology, Åbo Akademi University, Abo/Turku, Finland$$

[3]Laboratory of Physics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia$$Institute of Biophysics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia$$

[4]Laboratory of Physics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia$$

[5]Laboratory of Physics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia$$University College for Health Studies, University of Ljubljana, Ljubljana, Slovenia$$

关键词: Bilayer membranes;    Daughter vesicles;    Anisotropic membrane inclusions;   

DOI  :  10.2478/s11658-006-0009-3

学科分类：分子生物学，细胞生物学和基因

来源: Uniwersytet Wroclawski * Wydzial Biotechnologii / University of Wroclaw, Faculty of Biotechnology

【 摘 要 】

A theoretical model of a two-component bilayer membrane was used in order to describe the influence of anisotropic membrane inclusions on shapes of membrane daughter micro and nano vesicles. It was shown that for weakly anisotropic inclusions the stable vesicle shapes are only slightly out-of-round. In contrast, for strongly anisotropic inclusions the stable vesicle shapes may significantly differ from spheres, i.e. they have a flattened oblate shape at small numbers of inclusions in the membrane, and an elongated cigar-like prolate shape at high numbers of inclusions in the vesicle membrane.

【 授权许可】

Unknown