Cancer research in need of a scientific revolution: Using `paradigm shift’ as a method of investigation

Journal of biosciences

Meriwether Burruss¹  Boudewijn Van Der Sanden³  Didier Wion1³  François Berger³  Florence Appaix² 

[1] $$;the translation of the concepts issued from infectious disease in cancer research.$$;the reification of cancer as a tumour mass and$$

关键词: Cancer;    Koch’s postulates;    Kuhn;    micro-environment;    oncology;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Despite important human and financial resources and considerable accumulation of scientific publications, patents, and clinical trials, cancer research has been slow in achieving a therapeutic revolution similar to the one that occurred in the last century for infectious diseases. It has been proposed that science proceeds not only by accumulating data but also through paradigm shifts. Here, we propose to use the concept of `paradigm shift’ as a method of investigation when dominant paradigms fail to achieve their promises. The first step in using the `paradigm shift’ method in cancer research requires identifying its founding paradigms. In this review, two of these founding paradigms will be discussed:the reification of cancer as a tumour mass and

【 授权许可】

Unknown