A Model Immunization Programme to Control Japanese Encephalitis in Viet Nam

Journal of Health, Population and Nutrition (JHPN)

Kyung Park, Jin¹  Liu, Wei¹  V. Gibbons, Robert¹  Yoon Chang, Na¹  Xu, Zhi-yi¹  Anh Tuan, Pham¹  Nisalak, Ananda¹  Marks, Florian¹  Thu Yen, Nguyen¹  Anh Thu, Nghiem¹  Minh Hong, Nguyen¹  Duc Hanh, Hoang¹  Nhu Duong, Tran¹  Clemens, John D.¹ 

关键词: Contraception;    Family planning;    Under-five mortality;    Unmet need;    Nigeria;   

DOI  :  10.3329/jhpn.v33i1.3209

来源: International Centre for Diarrheal Disease Research, Bangladesh (ICDDR,B)

【 摘 要 】

In Viet Nam, an inactivated, mouse brain-derived vaccine for Japanese encephalitis (JE) has been givenexclusively to ≤5 years old children in 3 paediatric doses since 1997. However, JE incidence remainedhigh, especially among children aged 5-9 years. We conducted a model JE immunization programme toassess the feasibility and impact of JE vaccine administered to 1-9 year(s) children in 3 standard-dose regimen:paediatric doses for children aged <3 years and adult doses for those aged ≥3 years. Of the targetedchildren, 96.2% were immunized with ≥2 doses of the vaccine. Compared to the national immunizationprogramme, JE incidence rate declined sharply in districts with the model programme (11.32 to 0.87 per100,000 in pre- versus post-vaccination period). The rate of reduction was most significant in the 5-9 yearsage-group. We recommend a policy change to include 5-9 years old children in the catch-up immunizationcampaign and administer a 4th dose to those aged 5-9 years, who had received 3 doses of the vaccineduring the first 2-3 years of life. Key words: Demonstration project; Effectiveness study; Immunization; Japanese encephalitis; Vaccines

【 授权许可】

Unknown