One year in review 2015: systemic lupus erythematosus

Clinical and Experimental Rheumatology

Roberta Vagelli¹  Giulia Mirabelli¹  Francesca Cannarile¹  Linda Carli¹  Cosimo Bruni¹  Rossella De Luca¹ 

关键词: Systemic lupus erythematosus;    pathogenesis;    biomarkers;    clinical manifestations;    imaging;    patient reported outcome;    therapy;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

Systemic lupus erythematosus is a multiorgan autoimmune disease with a highly variable clinical course, typically involving women in childbearing age. At present, many aspects of its pathogenesis still remain unclear. Moreover, although a significant increase of patient survival has been observed in the last decades, morbidity and mortality remain high. Finally, SLE impacts negatively on the health-related quality-of-life of patients. Therefore, multiple aspects of SLE still remain challenging and it continues to be the object of both clinical and translational clinical research. Herewith, we provide a critical digest of the recent literature on this topic.

【 授权许可】

Unknown