期刊论文详细信息
FEBS Letters | |
The viral potassium channel Kcv: structural and functional features | |
DiFrancesco, Dario2  Lombardi, Mara3  Moroni, Anna3  Severino, Maria3  Gazzarrini, Sabrina3  Thiel, Gerhard1  Van Etten, James L4  Morandi, Marzia3  | |
[1] Membrane Biophysics, Botany Institute, Darmstadt University of Technology, Schnittspahnstrasse 3, 64287 Darmstadt, Germany;Department of General Physiology and Biochemistry, Università degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy;Department of Biology, CNR-IBF Unità di Milano, Università degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy;Department of Plant Pathology, University of Nebraska, Lincoln, NE 68583-0722, USA | |
关键词: K+ channel; Kcv; PBCV-1; Chlorella virus; | |
DOI : 10.1016/S0014-5793(03)00777-4 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The chlorella virus PBCV-1 was the first virus found to encode a functional potassium channel protein (Kcv). Kcv is small (94 aa) and basically consists of the M1-P-M2 (membrane-pore-membrane) module typical of the pore regions of all known potassium channels. Kcv forms functional channels in three heterologous systems. This brief review discusses the gating, permeability and modulation properties of Kcv and compares them to the properties of bacterial and mammalian K+ channels.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912020313343ZK.pdf | 243KB | download |