Component plane presentation integrated self‐organizing map for microarray data analysis

FEBS Letters

Zhang, Ji²  Wang, Kankan³  Teng, Yue¹  Xiao, Li² 

[1] Department of Pathology and Microbiology, University of Nebraska Medical Center, 985454 Nebraska Medical Center, Omaha, NE 68198, USA;Center for Human Molecular Genetics, MMI, University of Nebraska Medical Center, Omaha, NE, USA;State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai, PR China

关键词: Microarray data display;    Component plane;    Self-organizing map;    SOM;    self-organizing map;   

DOI  :  10.1016/S0014-5793(03)00156-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We describe a powerful approach, component plane presentation integrated self-organizing map (SOM), for the analysis of microarray data. This approach allows the display of multi-dimensional SOM outputs of microarray data in multiple sample specific presentations, providing distinct advantages in visual inspection of biological significances of genes clustered in each map unit with respect to each RNA sample. Beneficial potentials of the approach are highlighted by processing microarray data from yeast cells as well as human breast malignancies.

【 授权许可】

Unknown