Membrane properties of sphingomyelins

FEBS Letters

Ramstedt, Bodil¹  Slotte, J.Peter¹ 

[1] Department of Biochemistry and Pharmacy, Åbo Akademi University, P.O. Box 66, 20521 Turku, Finland

关键词: Cholesterol;    Lipid interaction;    Raft property;    Lipid miscibility;    Lateral heterogeneity;   

DOI  :  10.1016/S0014-5793(02)03406-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Sphingomyelin and phosphatidylcholine are important components in the external leaflet of cellular plasma membranes. In this review we compare the structure of these lipid molecules, with emphasis on the differences in hydrogen bonding capacity and membrane properties that arise from the small but significant differences in molecular structure. The membrane properties of sphingomyelins and the implications that these have, or might have, in biological membranes and for raft function are further discussed.

【 授权许可】

Unknown