The reduction potential of the β‐carotene +/β‐carotene couple in an aqueous micro‐heterogeneous environment

FEBS Letters

McGarvey, David J.¹  Land, Edward J.²  Truscott, T.George¹  Edge, Ruth¹  Burke, Marc¹ 

[1] School of Chemistry and Physics, Lennard-Jones Laboratories, Keele University, Keele, Staffordshire ST5 5BG, UK;CRC Section of Drug Development, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester M20 4BX, UK

关键词: β-Carotene;    Tryptophan;    Tyrosine;    Cysteine;    One-electron reduction potential;   

DOI  :  10.1016/S0014-5793(00)01366-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

There is a resurgence of interest in the role of electron transfer reactions involving β-carotene in photosynthesis. There is also current debate on the health benefits of dietary carotenoids and the possible deleterious effects on certain sub-populations such as smokers. The impact of dietary carotenoids on health may well be also related to radical reactions. A key parameter in biological systems is therefore the one-electron reduction potential of the carotenoid radical cation, now reported for the first time in a model biological aqueous environment. The value obtained is 1.06±0.01 V and is sufficiently high to oxidise cell membrane proteins, but is low enough to repair P₆₈₀ ⁺ in the photosynthetic reaction centre.

【 授权许可】

Unknown