Vertebrate pseudogenes

FEBS Letters

Robinson, P.A.¹  Mighell, A.J.¹  Smith, N.R.¹  Markham, A.F.¹ 

[1] Molecular Medicine Unit, The University of Leeds, Clinical Sciences Building, St. James's University Hospital, Leeds LS9 7TF, UK

关键词: Pseudogene;    Retrotransposon;    Human genome;    Transcription;   

DOI  :  10.1016/S0014-5793(00)01199-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Pseudogenes are commonly encountered during investigation of the genomes of a wide range of life forms. This review concentrates on vertebrate, and in particular mammalian, pseudogenes and describes their origin and subsequent evolution. Consideration is also given to pseudogenes that are transcribed and to the unusual group of genes that exist at the interface between functional genes and non-functional pseudogenes. As the sequences of different genomes are characterised, the recognition and interpretation of pseudogene sequences will become more important and have a greater impact in the field of molecular genetics.

【 授权许可】

Unknown