Involvement of ecto‐ATPase and extracellular ATP in polymorphonuclear granulocyte‐endothelial interactions

FEBS Letters

Sud'ina, Galina F¹  Mirzoeva, Olga K¹  Ullrich, Volker²  Galkina, Svetlana I¹  Pushkareva, Marina A¹ 

[1] A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow 119899, Russia;Faculty of Biology, University of Konstanz, 78457 Konstanz, Germany

关键词: Adhesion;    Ecto-ATPase;    ATP;    Collagen;    Fibronectin;    Suramin;    PMN;    polymorphonuclear granulocytes;    TNF;    tumor necrosis factor;    RB2;    Reactive Blue 2;    EHNA;    erythro-9-(2-hydroxy-3-nonyl)adenine;    Fn;    fibronectin;    HBSS;    Hanks' balanced salts solution with 10 mM HEPES;    pH 7.4;   

DOI  :  10.1016/S0014-5793(98)00102-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We conclude that PMN-endothelial adhesion is counteracted by an ecto-ATPase or by ATP receptors with ATPase activity. Such interactions may play a role in PMN rolling and diapedesis as well as in the pathophysiology of PMN activation by an anergic endothelium.

【 授权许可】

Unknown