期刊论文详细信息
FEBS Letters | |
Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin‐6 signal transducer gp130 | |
Diamant, Marcus1  Zhang, Xue-Guang2  Bendtzen, Klaus1  Svenson, Morten1  Klein, Bernard2  Mechti, Nadir2  Rieneck, Klaus1  | |
[1] Institute for Inflammation Research, Rigshospitalet, 7544, Tagensvej 20, DK-2200 Copenhagen N, Denmark;Institute of Molecular Genetics, CNRS, BP 5051, 1919 Route de Mende, 34033 Montpellier, France | |
关键词: gp130; Soluble receptor; Alternative splicing; | |
DOI : 10.1016/S0014-5793(97)00750-3 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
Both gp130 and alternatively spliced sgp130 were also transcribed by the myeloma cell lines XG-1, XG-2, XG-4, XG-4CNTF XG-6, XG-7, XG-9, XG-10, U266 and RPMI 8226. However, XG-4A cells derived from XG-4 cells, but growing independently of exogenous IL-6, did not transcribe sgp130 mRNA. A possible interference with intracrine stimulatory factors by alternatively spliced sgp130 needs to be further investigated.
【 授权许可】
Unknown
【 预 览 】
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