Bcl‐2 prevents nitric oxide‐mediated apoptosis and poly(ADP‐ribose) polymerase cleavage

FEBS Letters

Lee, Sean Bong²  Rodriguez, Dolores¹  Esteban, Mariano³  Mělková, Zora³ 

[1] Centro Nacional de Biotecnologı́a, CSIC, Campus Universidad Autónoma, 28049 Madrid, Spain;Department of Microbiology and Immunology, SUNY, Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY 11203, USA;Department of Biochemistry, SUNY, Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY 11203, USA

关键词: Nitric oxide;    Apoptosis;    Bcl-2;    PARP;    NO;    nitric oxide;    iNOS;    inducible nitric oxide synthase;    VV;    vaccinia virus;    WRNOS;    VV recombinant expressing iNOS;    WRbcl2;    VV recombinant expressing bcl2;    CAT;    chloramphenicol acetyltransferase;    WRCAT;    VV recombinant expressing CAT;    ROI;    reactive oxygen intermediate;    PARP;    poly(ADP-ribose) polymerase;    ICE;    interleukin-1β-converting enzyme;    HeLa G;    human cervical carcinoma cell line;    BSC-40;    African green monkey kidney epithelial cell line;    DMEM;    Dulbecco's modified Eagle medium;    NCS;    neonatal calf serum;    IPTG;    isopropyl-β-thiogalactoside;    PFU;    plaque forming unit;    h.p.i.;    hours postinfection;    TBARS;    thiobarbituric acid reactive substance;    GSH;    reduced glutathione;    NAC;    N-acetylcysteine;   

DOI  :  10.1016/S0014-5793(97)00065-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

© 1997 Federation of European Biochemical Societies.

【 授权许可】

Unknown