Fungal ferritins: The ferritin from mycelia of Absidia spinosa is a bacterioferritin

FEBS Letters

Matzanke, Berthold F.¹  Carrano, Carl J.¹  Böhnke, Rudi¹ 

[1] Microbiology and Biotechnology, University of Tübingen, Auf der Morgenstelle 1, 72076 Tübingen, Germany

关键词: Iron metabolism;    Ferritin;    Bacterioferritin;    Fungi;    Absidia spinosa;   

DOI  :  10.1016/0014-5793(96)00667-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Two distinct ferritin like iron containing proteins have been identified and isolated from the fungus Absidia spinosa; one from the spores and another from the mycelia. The mycelial protein has been purified and consists of two subunits of approx. 20 kDa. The N-terminal sequences of both subunits have been determined. The holoprotein as isolated contains approx. 750 iron atoms/molecule and exhibits a heme-like UV-Vis spectrum. Based on the heme spectrum and the high degree of sequence homology found, it has been established that the mycelial protein is a bacterioferritin. This is the first example demonstrating the presence of a bacterioferritin in a eukaryotic organism.

【 授权许可】

Unknown