Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins

FEBS Letters

Matsuda, Yoichi¹  Hensler, Patrick J.²  Mitsui, Youji³  Kaul, Sunil C.³  Komatsu, Yasuhiko³  Pereira-Smith, Olivia M.²  Wadhwa, Renu³ 

[1] Division of Genetics, National Institute of Radiological Sciences, Chiba, Japan;Roy M. and Phyllis Gough Huffington Center on Aging, Division of Molecular Virology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA;National Institute of Bioscience and Human Technology, AIST 1-1 Higashi, Tsukuba, Ibaraki 305, Japan

关键词: Mortalin;    Chromosomal assignment;    Mouse;    Human;   

DOI  :  10.1016/0014-5793(95)00177-B

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Mortalin has been shown to exhibit differential distributions in cells with mortal and immortal phenotypes. In the present study, we report mot-2 cDNA cloning from RS-4 cells — an immortal clone from CD1-ICR mouse embryonic fibroblasts — and the chromosomal assignments of mortalin related genes to mouse chromosomes 18 and X by fluorescence in situ hybridization. Similar analysis assigned the gene to chromosome 5q31.1 in human.

【 授权许可】

Unknown