Unique molecular properties of superoxide dismutase from teleost fish skin

FEBS Letters

Sato, Minoru¹  Takeuchi, Masaaki¹  Nakano, Toshiki¹ 

[1] Marine Biochemistry Laboratory, Faculty of Agriculture, Tohoku University, Aoba-ku, Sendai 981, Japan

关键词: Superoxide dismutase;    Molecular properties;    Thermostability;    Teleost;    Paralichthys olivaceus;    Fish skin;    SOD-Fs;    fish skin Cu;    Zn-SOD;   

DOI  :  10.1016/0014-5793(95)00084-M

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A unique Cu,Zn-SOD was found and isolated from plaice Paralichthys olivaceus skin. Surprisingly, the properties of purified fish skin SOD were very different from those of SOD from other sources reported so far. The purified SOD was composed of four same subunits of 16 kDa and the molecular weight of the native SOD was found to be around 65 kDa. The dominant amino acids of the SOD were Ser, Thr, Pro and Glu. Above 70°C, thermostability of the SOD was much lower than that of bovine erythrocyte Cu,Zn-SOD.

【 授权许可】

Unknown