Parallel β/α‐barrels of α‐amylase, cyclodextrin glycosyltransferase and oligo‐1,6‐glucosidase versus the barrel of β‐amylase: Evolutionary distance is a reflection of unrelated sequences

FEBS Letters

Janeček, Štefan¹ 

[1] Institute of Ecobiology, Slovak Academy of Sciences, Štefánikova 3, SK-81434 Bratislava, Slovakia

关键词: Parallel β/α-barrel fold;    α-Amylase enzyme superfamily;    β-Amylase;    Sequence similarities;    Structure comparison;    Evolutionary relationships;    AMY;    α-amylase;    BMY;    β-amylase;    CGT;    cyclodextrin glycosyltransferase;    GMY;    gluco-amylase;    OGL;    oligo-1;    6-glucosidase;    TIM;    triosephosphate isomerase;   

DOI  :  10.1016/0014-5793(94)01019-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The structures of functionally related β/α-barrel starch hydrolases, α-amylase, β-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, are discussed, their mutual sequence similarities being emphasized. Since these enzymes (except for β-amylase) along with the predicted set of more than ten β/α-barrels from the α-amylase enzyme superfamily fulfil the criteria characteristic of the products of divergent evolution, their unrooted distance tree is presented.

【 授权许可】

Unknown