Calcium is necessary in the cell response to EM fields

FEBS Letters

Shalts, Natalia¹  Broude, Natasha¹  Goodman, Reba²  Henderson, Ann S.¹  Karabakhtsian, Rouzan¹  Kochlatyia, Serguei¹ 

[1] Department of Biological Sciences, Hunter College and the Graduate Divisions in Biology and Biochemistry of the City University of New York, 695 Park Ave., New York, NY 10021, USA;Department of Pathology, Columbia University Health Sciences, New York, NY 10032, USA

关键词: Extremely low frequency (elf) electromagnetic (EM) fields;    Calcium;    RNA transcript;    EM;    electromagnetic;    elf;    extremely low frequency;    B;    magnetic field;    E;    electric field;   

DOI  :  10.1016/0014-5793(94)00618-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Previous research showed that exposure of human HL-60 cells to extremely low frequency electromagnetic fields increases the steady-state levels of some mRNAs. Modifications in calcium flux have been suggested as a means of amplifying electromagnetic signals, and induced changes in calcium influx could hypothetically lead to gene activation. The present experiments tested the role of calcium in the response of cells to electromagnetic fields. Steady state transcript levels for c-fos and c-myc were determined under conditions of low extracellular calcium. The present study confirms that calcium plays a role in the response of cells to electromagnetic fields.

【 授权许可】

Unknown