Small GTP‐binding proteins of squid photoreceptor

FEBS Letters

Artamonov, Igor D.¹  Petrov, Vasily M.¹  Lipkin, Valery M.¹ 

[1] Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul.Miklukho-Maklaya, 16110, 117871 GSP Moscow V-437, Russian Federation

关键词: GTP-binding protein;    Rhodopsin;    C3 ADP-ribosyltransferase;    Invertebrate vision;   

DOI  :  10.1016/0014-5793(94)80207-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Squid photoreceptor membranes contain several small GTP-binding proteins (22–27 kDa) in addition to heterotrimeric G-proteins. In addition, these membranes contain several proteins which can be ADP-ribosylated by exoenzyme C₃ from Clostridium botulinum (C₃). These proteins are similar but not identical to C₃ substrates from bovine rod outer segments. It is shown that substrates of C₃ in squid photoreceptor interact with rhodopsin in a light-dependent manner. These data suggest involvement of small GTP-binding proteins in phototransduction processes in invertebrates.

【 授权许可】

Unknown