Retinal oxidase is identical to aldehyde oxidase

FEBS Letters

Ichikawa, Yoshiyuki¹  Tsujita, Maki¹  Tomita, Shuhei¹ 

[1] Department of Biochemistry, Kagawa Medical School, Miki-cho, Kita-gun, Kagawa 761-07, Japan

关键词: Retinal oxidase;    Aldehyde oxidase;    Retinoic acid synthase;    Flavoenzyme;    Oxidoreductase;    NMNA;    N-methylnicotinamide;    NBT;    Nitro blue tetrazolium;    DCIP;    dichlorophenolindophenol;   

DOI  :  10.1016/0014-5793(93)80818-F

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Retinal oxidase (EC 1.2.3.11) and aldehyde oxidase (EC 1.2.3.1) were compared with respect to their enzymatic and physicochemical properties. It was found that the molecular weights, subunits, optical spectra, chemical and immunological properties, cellular localization and substrate specificities of the two oxidases are identical on almost all points. The physiological function of aldehyde oxidase appears to be the synthesis of retinoic acid from retinal.

【 授权许可】

Unknown