Free hydroxyl radicals are formed on reaction between the neutrophil‐derived species Superoxide anion and hypochlorous acid

FEBS Letters

Candeias, Luis P.¹  Wardman, Peter¹  Stratford, Michael R.L.¹  Patel, Kantilal B.¹ 

[1] Cancer Research Campaign Gray Laboratory, PO Box 100, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, UK

关键词: Hypochlorous acid;    Superoxide anion;    Hydroxyl radical;    Radiolysis;   

DOI  :  10.1016/0014-5793(93)80394-A

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Superoxide anion reacts with hypochlorous acid to yield free hydroxyl radicals, as shown by the hydroxylation of benzoate. This reaction is analogous to the Haber-Weiss reaction but in the absence of metal ions is at least six orders of magnitude faster.

【 授权许可】

Unknown