Time‐dependoent increases in Na+,K+‐ATPase content of low‐frequency‐stimulated rabbit muscle

FEBS Letters

Dux, L.¹  Chin, E.R.²  Pette, D.¹  Ball-Burnett, M.²  Green, H.J.² 

[1] Fakultat für Biologie, Universität Konstanz, D-7750 Konstanz, Germany;Department of Kinesiology, University of Waterloo, Waterloo, Ont. N2L 3G1, Canada

关键词: Low-frequency stimulation;    Muscle fatigue;    Na+/K+-ATPase;    Sarcolemma;   

DOI  :  10.1016/0014-5793(92)81312-A

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Chronic low-frequency stimulation of rabbit fast-twitch muscle induced time-dependent increases in the concentration of the sarcoleminal Na⁺,K⁺-ATPase and in mitochondrial citrate synthase activity. The almost twofold increase in Na⁺,K⁺-ATPase preceded the rise in citrate synthase and was complete after 10 days of stimulation, We suggest that the increase in Na⁺,K⁺-ATPase enhances resistance to fatigue of low-frequency-stimulated muscle prior to elevations in aerobic-oxidative capacity.

【 授权许可】

Unknown